Toward innovative veterinary nanoparticle vaccines

Animal Diseases

Table 1 Overview of natural self-assembled peptide nanoparticles

Scaffold platform	Structure	Size	Development stage	Antigenic components displayed	Expression system	Reference
Ferritin	Octahedral symmetry (24 subunits)	12 nm	Phase 1 clinical trials	CSFV E2	BEVS	Zhao et al. 2021; Chen et al. 2020; Kanekiyo et al. 2013; Yassine et al. 2015; Ma et al. 2021)
				FMDV VP1	BEVS
				H1N1 HA	HEK293 mammalian cells
				PRRSV GP5	BEVS

Abbreviations: CSFV classical swine fever virus, BEVS Baculovirus expression vector system, PRRSV Porcine reproductive and respiratory syndrome virus, FMDV Foot-and-mouth disease virus