Fig. 2

Effect of L.j or L.m on colonic barrier function in LPS-challenged piglets. A Colonic morphological structure after H&E staining. Images of colonic morphology (scale bar = 200 or 50 μm). B Colonic histopathological score. C Colonic ZO-1 and Occludin protein expression. Colonic ZO-1 (D) and Occludin (E) protein expression analysis. The data are presented as the means ± SEMs (n = 8 for A and B; n = 4 for C–E). Differences between the LPS and CON groups, ***P < 0.001. Differences between the LPS + L. j or LPS + L. m group and the LPS group, ##P < 0.01; ##P < 0.001. CON, control; H&E, hematoxylin and eosin; L. j, Limosilactobacillus johnsoni; L. m, Limosilactobacillus mucosae; LPS, lipopolysaccharide