Fig. 3

Effects of TDCA on diquat-induced oxidative stress in the jejunum and the expression of intestinal barrier function-related proteins in mice. A Nrf2, ZO-1, and Occludin protein expression was analyzed via western blotting in the CON, DQ, and DQ + TDCA (15) groups. B-D Expression of the Nrf2, ZO-1 and Occludin proteins in each group. n = 3. All the data are presented as the means ± SEMs. When the DQ group was compared with the CON group, **P < 0.01, ***P < 0.001, ****P < 0.0001; when the DQ + TDCA (15) group was compared with the DQ group, ##P < 0.01, ###P < 0.001, ####P < 0.0001. CON, control; DQ, diquat; TDCA, taurodeoxycholic acid; Nrf2, nuclear factor erythroid 2-related factor 2; TDCA (15) indicates treatment with 15 mg/kg TDCA