Fig. 7

TDCA alleviates diquat-induced intestinal barrier injury in mice through the Nrf2 pathway. A ZO-1 and Occludin protein expression was analyzed by western blot in the CON, DQ + TDCA, and DQ + TDCA + ML385 groups. B-C ZO-1 and Occludin protein expression in each group. n = 3. All the data are presented as the means ± SEMs. ***P < 0.001, ****P < 0.0001 indicates between-group comparisons. CON, control; DQ, diquat; TDCA, taurodeoxycholic acid; ML385, specific Nrf2 inhibitor; TDCA (15) indicates treatment with 15 mg/kg TDCA