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Fig. 4 | Animal Diseases

Fig. 4

From: Characterization of two neutralizing monoclonal antibodies with conformational epitopes against porcine deltacoronavirus

Fig. 4

Epitope mapping of the mAbs. (A) Schematic shows PDCoV-S variants for epitope mapping, divided into nine segments. The PDCoV S (PDB 6BFU) structural diagram is displayed, with different domains highlighted by distinct colors. (B) IFA detected 1C2/5H5 binding to BHK-21 cells transfected with truncated PDCoV-S plasmids. Magnification, × 100. IFA (C) and western blot (D) were used to detect the expression of Myc-tagged S1 variants. (E) Summary of antibody binding to truncated S proteins: " + " = positive, "-" = negative

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Animal Diseases

ISSN: 2731-0442