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  1. Streptococcus suis (S. suis) is a major zoonotic pathogen whose nasopharyngeal colonization relies on adaptive regulation in response to the host’s low-glucose microenvironment. However, the molecular mechanisms ...

    Authors: Ran Liu, Shulin Miao, Kunlong Xia, Yuhua Wang, Long Li and Anding Zhang
    Citation: Animal Diseases 2025 5:17
    Content type: Original Article Published on:

  3. Feline herpesvirus type 1 (FHV-1) is a common and highly contagious pathogen in domestic cats that causes upper respiratory tract infections and ocular diseases. Accurate and rapid diagnosis of FHV-1 infection...

    Authors: Jianzhong Wang, Jicheng Qiu, Yiduo Liu, Xianglin Ma, Xiaojie Wu, Xiaoguang Li and Wei Mao
    Citation: Animal Diseases 2025 5:15
    Content type: Original Article Published on:

  4. Coinfection, the simultaneous invasion of multiple pathogens into a single host, is a critical but understudied area, especially in the farm animal sector. We report a unique and unusual fatal case of coinfect...

    Authors: Qianzhe Cao, Chenghao Jia, Haiyang Zhou, Hongli An, Chenghu Huang, Xiaolei Wu, Xiamei Kang, Yingying Huang, Fang He, Yan Li and Min Yue
    Citation: Animal Diseases 2025 5:14
    Content type: Short Communication Published on:

  6. This report describes the first documented case of Mycobacterium caprae (M. caprae) infection in a domestic cat (Felis catus) in the United Kingdom. The affected cat was a male-castrated Bengal breed that present...

    Authors: Cecilia Gola, Javier Déniz Marrero, Sai Fingerhood, Marta Hernández Pérez and Pablo Díaz Santana
    Citation: Animal Diseases 2025 5:12
    Content type: Case Report Published on:

  7. Feline injection site sarcomas (FISSs) are tumors frequently found at injection sites in domestic cats associated with vaccines and other pharmaceutical substances. The most accepted theory suggests that chron...

    Authors: Helena Gomes, Rita Files, Gabriela Maia, Ana Vidal, Maria Silva, Justina Prada, Isabel Pires and Filipe Silva
    Citation: Animal Diseases 2025 5:11
    Content type: Short Communication Published on:

  8. Pseudorabies virus (PRV, SuidAlphaherpesvirus 1) causes substantial economic losses in swine production. Here, we report the development of DNA aptamers targeting the PRV glycoprotein D (gD) through an optimized ...

    Authors: Zhihao Wang, Yan Qiao, Jiafu Zhao, Xiaotian Chang, Heshui Zhu and Chao Zhang
    Citation: Animal Diseases 2025 5:10
    Content type: Original Article Published on:

  9. Fowl adenovirus (FAdV) serotype 4, recognized as the causative agent of hydropericardium syndrome (HPS) in chickens, causes substantial economic losses in poultry farming. To develop a simple, rapid, and relia...

    Authors: Xinhua Zhang, Yulin Zhan, Hao Wu, Ping Zhou, Yumei Fu, Lun Yao and Duo Fang
    Citation: Animal Diseases 2025 5:9
    Content type: Original Article Published on:

  10. Porcine epidemic diarrhea virus (PEDV) is a highly infectious intestinal coronavirus that poses a significant threat to the pig industry because of its strong virulence and propensity for mutation and recombin...

    Authors: Yiye Zhang, Jiahui Guo, Qi Yang, Tong Zhuang, Shaobo Xiao and Liurong Fang
    Citation: Animal Diseases 2025 5:8
    Content type: Original Article Published on:

  11. Porcine epidemic diarrhea (PED), caused by porcine epidemic diarrhea virus (PEDV), can induce 80–100% mortality in newborn piglets; therefore, specific and rapid detection methods are important for the prevent...

    Authors: Jiakai Zhao, Lu Zhang, Yibo Kong, Miao Dan, Yangzong Xiri, Pinpin Ji, Shijin Jiang, Yani Sun and Qin Zhao
    Citation: Animal Diseases 2025 5:7
    Content type: Original Article Published on:

  13. The contamination of pork during breeding can negatively impact both food quality and safety. Sodium dichloroisocyanurate (NaDCC), a chlorine-containing disinfectant, is widely used in animal environments. In ...

    Authors: Feng Liu, Jiele Ma, Lichang Sui, Wen Wang, Yingping Xiao, Qingli Dong and Xingning Xiao
    Citation: Animal Diseases 2025 5:5
    Content type: Original Article Published on:

  14. Cocktail therapy significantly reduces the development of resistance to individual medications due to viral mutations. However, for effective inhibition of a particular virus, a customized approach to combinat...

    Authors: Yingge Zheng, Yanfei Zhang, Fangying Xiong, Dehua Luo, Yuxiang Wang, Yijia Zhang and Dengguo Wei
    Citation: Animal Diseases 2025 5:4
    Content type: Original Article Published on:

  15. Lumpy skin disease (LSD) poses a significant threat to cattle populations and the livelihoods of farmers in Thailand. This study uses path analysis to explore the interrelationships among the knowledge, attitu...

    Authors: Sohrab Khan, Darawan Addoddon, Jutamas Prapapanpong, Minta Suwannaboon, Orapun Arjkumpa, Kannika Na-Lampang, Warangkhana Chaisowwong, Supitchaya Srisawang and Veerasak Punyapornwithaya
    Citation: Animal Diseases 2025 5:3
    Content type: Original Article Published on:

  16. Porcine deltacoronavirus (PDCoV) is a globally distributed swine enteropathogenic virus that emerged in the last decade. A recent report of PDCoV infection in Haitian children also highlights potential public ...

    Authors: Wan Lu, Hongtao Cao, Yongle Yang, Yangyang Sun, Dong Yang, Priscilla F. Gerber, Xiangdong Li, Yaowei Huang and Bin Wang
    Citation: Animal Diseases 2025 5:2
    Content type: Original Article Published on:

  17. Encephalomyocarditis virus (EMCV), a potential zoonotic pathogen, poses significant socioeconomic and public health challenges across various host species. Although EMCV rarely triggers severe clinical symptom...

    Authors: Yanfang Zhang, Zhiying Wang, Yaohui Fang, Qiong Zhu, Jie Fu, Sijing Hu, Jiayin Jin, Min Zhou, Xijia Liu, Danna Zhang, Shouwei Huang, Yali Deng, Lingling Xie, Shu Shen, Jing Ye, Fei Deng…
    Citation: Animal Diseases 2025 5:1
    Content type: Original Article Published on:

  18. Sheep and goat coccidiosis has a worldwide distribution and is an important disease on lambing farms. Infection with multiple Eimeria species can lead to severe intestinal damage in sheep/goats and economic losse...

    Authors: Manyu Liu, Senyang Li, Shucheng Huang, Longxian Zhang and Fuchun Jian
    Citation: Animal Diseases 2024 4:48
    Content type: Review Published on:

  19. Porcine reproductive and respiratory syndrome virus (PRRSV) has emerged as a significant threat to the pig farming industry worldwide, resulting in considerable economic losses. However, few reports detail its...

    Authors: Huifeng Zhao, Jingwei Zhou, Min Zhang, Xiutao Yang, Zhaofang Xi, Qingxia Gao, Rui Fang, Pengfei Zhao and Junlong Zhao
    Citation: Animal Diseases 2024 4:47
    Content type: Original Article Published on:

  20. Small ruminants are vital to the economy of Ethiopia and significantly contribute to the livelihoods of resource-poor farmers. However, poor management practices and high mortality rates among young lambs and ...

    Authors: Redwan Anwar, Rahmeto Abebe and Desie Sheferaw
    Citation: Animal Diseases 2024 4:46
    Content type: Original Article Published on:

  21. Pathogenic African swine fever virus (ASFV) remains a lethal causative agent in the domestic pig industry, which poses a burden on the swine market and causes substantial socioeconomic losses worldwide. Curren...

    Authors: Wenjing Xiong, Haowei Chen, Yanru Chen, Ke Wang, Tingting Lian, Weijia Zhang, Qing Yu, Xiaochen Gao, Jie Su, Qigai He, Xiangru Wang, Junping Yu and Min Cui
    Citation: Animal Diseases 2024 4:45
    Content type: Original Article Published on:

  22. Apicomplexan parasites predominantly generate ATP and lactic acid through glycolysis and anaerobic glucose metabolism, incorporating CO2 into glycolysis via a stage-dependent phosphoenolpyruvate carboxylase (PEPC...

    Authors: Dong-Fang Li, Ling-Na Wang, Yi-Dan Bai, Yu-Xin Yu, Xing Lu, Xing-Ai Guan, Fang-Jie Li, Sen Wang, Lan He and Jun-Long Zhao
    Citation: Animal Diseases 2024 4:44
    Content type: Original Article Published on:

  23. Gastrointestinal (GI) parasites are a global concern and cause serious damage to the health of animals, including horses, because of their deleterious effects on the health of these animals. Owing to improperl...

    Authors: J. G Golshang, N Nanvyat, E. R Edeh, M. N Patrobas, D. O Oshadu, C. H Dishion, A. A Dzikwi-Emennaa, E. O Otakpa, G. N Imandeh and L. H Lombin
    Citation: Animal Diseases 2024 4:43
    Content type: Original Article Published on:

  24. Frequent extreme heat events around the world not only pose a major threat to human health but also cause significant economic losses to the livestock industry. The existing management practices are insufficie...

    Authors: Hanfei Wang, Shuyi Xu, Haiyang Mao, Boyu Wang, Yanping Feng, Awais Ihsan, Shijun Li and Xu Wang
    Citation: Animal Diseases 2024 4:42
    Content type: Original Article Published on:

  25. Muscular atrophy accompanied by neuromuscular junction (NMJ) denervation is often observed after long-term chronic diseases and aging and is associated with substantial morbidity and mortality. Here, we report...

    Authors: Ying Jin, Wei Kang, Xiaoge Ji, Yihao Zhou and Ling Zheng
    Citation: Animal Diseases 2024 4:41
    Content type: Original Article Published on:

  26. Seasonal influenza A virus (IAV), particularly the H1N1 subtype, poses a significant public health threat because of its substantial morbidity and mortality rates worldwide. Understanding the immune response t...

    Authors: Yu Chen, Huaiyuan Cai, Qian Zhang, Gang Cao, Jiahao Zhang, Bing Yang and Jinxia Dai
    Citation: Animal Diseases 2024 4:40
    Content type: Original Article Published on:

  27. Pullorum disease and fowl typhoid are caused by the Salmonella serovars Gallinarum biovars Pullorum and Gallinarum, respectively. The prevalence of these diseases varies across regions and is affected by differen...

    Authors: Xiamei Kang, Canghong Jin, Pengkun Gu, Song Wang, Zhengjie Gao, Chenyi Dai, Xiao Zhou, Abubakar Siddique, Haiyang Zhou, Linlin Huang, Yan Li and Min Yue
    Citation: Animal Diseases 2024 4:39
    Content type: Original Article Published on:

  28. It is important to consider the full spectrum of complex interactions between mineral elements and biologically active substances to evaluate the development of cardiovascular disease (CVD) in animals, in addi...

    Authors: Sergei Yu. Zaitsev, Marina V. Stepanova and Larisa F. Sotnikova
    Citation: Animal Diseases 2024 4:38
    Content type: Original Article Published on:

  29. The gastrointestinal tract of felines is inhabited by an active and intricate population of microorganisms whose alteration creates disturbances in the immune response and can affect health and disease states....

    Authors: Yuejun Shi, Guiqing Peng, Ashenafi Assefa Gebremariam, Muhammad Muazzam Iqbal, Hakimeh Baghaei Daemi, Muhammad Ali Khan, Rizwan Ullah and Donghan Wang
    Citation: Animal Diseases 2024 4:36
    Content type: Review Published on:

  31. Emerging infectious diseases are a major threat to biodiversity and an important public health issue. Flaviviruses are the cause of several emerging vector-borne zoonotic arboviruses whose distribution is curr...

    Authors: Filipa Loureiro, Luís Cardoso, Ana C. Matos, Cristina Pintado, Filipe Silva, Mariana Ferreira, Ricardo Brandão, Carolina Lopes, Ana Patrícia Lopes, João Rodrigo Mesquita, Manuela Matos and Ana Cláudia Coelho
    Citation: Animal Diseases 2024 4:35
    Content type: Short Communication Published on:

  32. Oxidative stress is an important contributor to gastrointestinal diseases in multiple ways. Taurodeoxycholic acid (TDCA) is a metabolite of bile acids and has anti-inflammatory and protective effects on the in...

    Authors: Jinglei Liu, Yuhan Zhang, Mengzhen Song, Xuming Guo, Jinping Fan and Shiyu Tao
    Citation: Animal Diseases 2024 4:34
    Content type: Original Article Published on:

  33. African swine fever (ASF) is a highly fatal hemorrhagic disease affecting domestic pigs caused by African swine fever virus (ASFV). Genetic analysis of ASFV isolates to date has identified 24 geographically re...

    Authors: Xuexiang Yu, Haowei Wu, Dongfan Li, Qian Xu, Xiaoyu Chen, Chengjun Zhang, Fengqin Xu, Xugang Ku, Qigai He and Wentao Li
    Citation: Animal Diseases 2024 4:33
    Content type: Short Communication Published on:

  34. Porcine reproductive and respiratory syndrome (PRRS) is a severe threat to pig farming worldwide and contributes to substantial financial losses. Endogenous short RNAs, known as microRNAs (miRNAs), play variou...

    Authors: Yu-Chen Wang, Zhi-Yong Shao, Wei-Xue Yi, Li-Jun Wu, Wei Liu, Xia-Bing Chen, Rui-Ge Cao and Bin He
    Citation: Animal Diseases 2024 4:32
    Content type: Review Published on:

  35. Trained immunity is a phenomenon in which brief exposure to an infectious agent or a vaccine can induce long-lasting changes in the host's immune system, enhancing protection against subsequent infections. The...

    Authors: Md. Salauddin, Sabuj Kanti Nath, Sukumar Saha, Qingcong Zheng, Chunfu Zheng and Md. Golzar Hossain
    Citation: Animal Diseases 2024 4:31
    Content type: Review Published on:

  36. Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus that can cause acute diarrhea and vomiting in newborn piglets and poses a potential risk for cross-species transmission. It is...

    Authors: Wei Wang, Baochao Fan, Xuehan Zhang, Shanshan Yang, Junming Zhou, Rongli Guo, Yongxiang Zhao, Jinzhu Zhou, Jizong Li and Bin Li
    Citation: Animal Diseases 2024 4:30
    Content type: Short Communication Published on:

  38. Single B-cell antibody generation technology is an advanced method that offers several advantages, including rapid production, high efficiency, and high yield. The antibodies generated via this technique retai...

    Authors: Zhengxin Yang, Fangtao Li, Mengjia Zhang, Yan Li, Qizu Zhao, Chunyan Wang, Lu Xu, Yebing Liu, Wentao Li and Yuanyuan Zhu
    Citation: Animal Diseases 2024 4:28
    Content type: Short Communication Published on:

  39. The Nyctereutes procyonoides is highly regarded in the farming and leather industries because of the high value of its fur, which renders artificial feeding a crucial aspect. However, high-fat diets have always b...

    Authors: Zhaoming Li, Chengwei Wei, Jie Yang, Yuan Geng, Mengran Zhu, Tianchao Xu and Mengyao Guo
    Citation: Animal Diseases 2024 4:27
    Content type: Original Article Published on:

  40. The recent Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic highlights the significant threat coronaviruses (CoVs) pose to public health. With their extensive cross-continental movements, ...

    Authors: Yingjie Lian, Ying Huang, Lixia Xie, Quan Liu, Zhengkai Wei, Runfeng Shi, Xinhong Pan, Wenfen Zhang, Jun Ma and Juntao Li
    Citation: Animal Diseases 2024 4:26
    Content type: Short Communication Published on:

  42. African swine fever (ASF) is an acute and fatal hemorrhagic disease in domestic pigs and wild boars caused by African swine fever virus (ASFV) that currently threatens the pig industry worldwide. Since the 201...

    Authors: Jiajia Zhang, Yuening Wang, Kaili Zhang, Dafu Deng, Kai Peng, Wanglong Zheng, Nanhua Chen, Penggang Liu, Shaobin Shang, Ruichao Li and Jianzhong Zhu
    Citation: Animal Diseases 2024 4:24
    Content type: Original Article Published on:

  43. Lumpy skin disease (LSD) is a highly contagious disease caused by lumpy skin disease virus (LSDV) in bovines. Rapid and accurate diagnosis is very important to controll it. However, current commercial detectio...

    Authors: Xinwei Yuan, Hui Zhao, Wanfeng Ji, Xiaohan Yan, Zhijie Xiang, Li Yang, Yuanchen Geng, Yingyu Chen, Jianguo Chen, Xi Chen, Lei Zhang, Changmin Hu and Aizhen Guo
    Citation: Animal Diseases 2024 4:23
    Content type: Original Article Published on:

  44. Mycobacterium tuberculosis (Mtb) employs multiple mechanisms, such as phagocytosis and autophagy, to evade innate immune clearance and establish infection. In the present study, we identified the ESX-1 secretion-...

    Authors: Luxia Cai, Yingying Lei, Tianyi Xie, Yiling Liu, Yutong Fan, Bing Yang, Shuang Dong, Gang Cao and Xi Chen
    Citation: Animal Diseases 2024 4:22
    Content type: Short Communication Published on:

  45. We report the development of a triplex nucleic acid lateral flow immunoassay (NALFIA) for the detection of the genomes of Nipah virus (NiV), Middle East respiratory syndrome coronavirus (MERS-CoV) and Reston e...

    Authors: Santhalembi Chingtham, Diwakar D. Kulkarni, Sumi Sivaraman, Anamika Mishra, Atul K. Pateriya, Vijendra Pal Singh and Ashwin Ashok Raut
    Citation: Animal Diseases 2024 4:21
    Content type: Original Article Published on:

  46. Lactobacillus species have excellent abilities to reduce intestinal inflammation and enhance gut barrier function. This study elucidated the potential mechanisms through which Lactobacillus mitigates lipopolysacc...

    Authors: Yong Yao, Yuhan Zhang, Mengzhen Song, Jinping Fan, Shengkai Feng, Jingjing Li, Zhifeng Wu, Bo Zuo, Shiyu Tao and Xiangdong Liu
    Citation: Animal Diseases 2024 4:20
    Content type: Original Article Published on:

  48. African swine fever (ASF), caused by the ASF virus (ASFV), is an acute, severe, and highly contagious infectious disease in domestic pigs and wild boars. Domestic pigs infected with a virulent ASFV strain can ...

    Authors: Changjiang Weng
    Citation: Animal Diseases 2024 4:18
    Content type: Review Published on:

    The Correction to this article has been published in Animal Diseases 2024 4:29

  49. The prevalence of bacterial digestive diseases in plateau animals has caused considerable losses to the Tibetan livestock industry. Therefore, this study aimed to isolate safe lactic acid bacteria (LAB) with b...

    Authors: Yuanyuan He, Feiran Li, Mengen Xu, Chao Jin, Yu Zhang, Shah Nawaz, Muhammad Fakhar-e-Alam Kulyar, Mudassar Iqbal, Zhen Qin and Jiakui Li
    Citation: Animal Diseases 2024 4:17
    Content type: Original Article Published on:

  50. Bordetella bronchiseptica (Bb) is recognized as a leading cause of respiratory diseases in dogs and cats. However, epidemiological data on Bb in dogs and cats in China are still limited, and there is no commercia...

    Authors: Qinghua Shang, Wenhui Gao, Xiangting Zhang, Jianqing Zhao, Ying Wu, Haoqi Li, Ming Zhou, Zhen F. Fu, Chengguang Zhang and Ling Zhao
    Citation: Animal Diseases 2024 4:16
    Content type: Original Article Published on:
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Source Normalized Impact per Paper (SNIP): 0.870
SCImago Journal Rank (SJR): 0.529

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Animal Diseases accepts the following article types: 
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Huazhong Agricultural University (HZAU) is a national key university of “Project 211” directly under the Ministry of Education. HZAU enjoys a history of 120 years, covers an area of 495 hectares, and consists of 18 colleges and departments. Featuring life science, HZAU also gives much emphasis on the rational disciplinary construction of agriculture, sciences, engineering, arts, law, economics, and management.

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The National Key Laboratory of Agricultural Microbiology was founded by Chen Hua-Kui, a pioneering scientist in Chinese soil microbiology in 1990. It has consistently received excellent ratings in evaluations by the Ministry of Science and Technology for national key laboratories and outstanding departmental key laboratories in the field of life sciences in 1996, 2001, 2006, 2011 and 2016. In 2022, it was successfully recombined and approved as the "National Key Laboratory of Agricultural Microbiology". The lab focuses on varies of research areas, including the exploration of agricultural microbes, microbial structure and function, microbe‒host‒environment interactions, improvements in agricultural microbes, the development of new agricultural microbial products and food security.

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